Sabtu, 27 Februari 2010

[H293.Ebook] Ebook Free Mechanisms of Memory, by J. David Sweatt

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Mechanisms of Memory, by J. David Sweatt

This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms.

* Presents a unified view of memory mechanisms from behavior to genes and drawing examples from many different brain regions, types of learning, and various animal model systems
* Includes numerous practical examples for the new investigator on how to implement research program in the area of learning and memory
* Provides a balanced treatment of the strengths and weaknesses in modern experimental design

  • Sales Rank: #3523665 in Books
  • Published on: 2003-10-30
  • Original language: English
  • Number of items: 1
  • Dimensions: .79" h x 7.26" w x 10.20" l,
  • Binding: Hardcover
  • 350 pages

Review
"The book is well written and includes interesting and illustrative text inserts as well as colorful fugures with detailed explanations. Mechanisms of Memory is a successful integration of recent discoveries and technological advances applied to learning and memory at many different levels that will appeal to its target audience of advanced undergraduates and graduates across a number of disciplines."
--AMERICAN JOURNAL OF PSYCHIATRY (November 2005, 162:11)

"This is an exceptional book in more than one aspect. David Sweatt has written a monograph in which long term potentiation (LTP) is central issue. However, this book is not an endless presentation of all the numerous experiments into a context of learning and memory...the book presents a real opportunity for the advanced student, and the interested scientists, to learn more about LTP and how to put it into a perspective...The illustrations in the book are of high quality, informative and to the point. Every chapter is introduced at an abstract level, the last item I wanted to mention which makes this a special book, bringing long term reminiscences of Rothko and Pollock."
- Journal of Chemical Neuroanatomy (2005)

From the Back Cover

Mechanisms of Memory, second edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology to the molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, such as mental retardation syndromes and Alzheimer's Disease. Written in a readable and engaging style, the book emphasizes results from the cutting edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics, and molecular structure.

The book draws numerous examples from the recent experimental literature, and has as a unifying theme the modern hypothesis-testing approach to basic research. As such, the book provides a foundation of experimental design that should be useful to all students pursuing an interest in laboratory research. In addition, active researchers in the learning and memory field will benefit from its extensive review of recent publications in the area, cross-references to detailed recent reviews, and from the cross-disciplinary approach used in writing the book.

  • Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design
  • Extensively illustrated throughout with many new, full color figures and photographs to help explain key concepts
  • Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008)
  • A companion website provides figures in PowerPoint format plus additional, detailed further reading references

About the Author
David Sweatt obtained his B.S. in Chemistry from the University of South Alabama before attending Vanderbilt University, where he was awarded a Ph.D. for studies of intracellular signaling mechanisms. He then did a post-doctoral Fellowship at the Columbia University Center for Neurobiology and Behavior, working on memory mechanisms in the laboratory of Nobel laureate Eric Kandel. From 1989 to 2006 he was a member of the Neuroscience faculty at Baylor College of Medicine in Houston, Texas, rising through the ranks there to Professor and Director of the Neuroscience Ph.D. program. Dr. Sweatt’s laboratory studies biochemical mechanisms of learning and memory. In addition, his research program also investigates mechanisms of learning and memory disorders, such as mental retardation and aging-related memory dysfunction. He is currently the Evelyn F. McKnight endowed Chairman of the Department of Neurobiology at UAB Medical School, and the Director of the Evelyn F. McKnight Brain Institute at the University of Alabama in Birmingham. He also is a Professor the Departments of Cell Biology, Genetics, and Psychology at UAB. Dr. Sweatt has won numerous awards and honors, including an Ellison Medical Foundation Senior Scholar Award, and election as a Fellow of the American Association for the Advancement of Science. This year he won (along with Michael Meaney and Catherine Dulac) the Ipsen Foundation International Prize in Neural Plasticity, one of the most prestigious awards in his scientific field. From 1998 until 2002 he attended drawing and painting classes at the Glassell School of Art of the Museum of Fine Arts, Houston. As an artist he explores the use of painting as a medium for expressing topics of interest in contemporary biomedical research. In 2009 he published a textbook, Mechanisms of Memory, which is illustrated with original paintings and describes current models for the molecular and cellular basis of memory formation.

Most helpful customer reviews

2 of 2 people found the following review helpful.
Mechanisms of Memory
By The Rubes
Intermediate level introduction to concepts in learning and memory, and long term potentiation of the hippocampus. Written in a clear and personal style, covers many of the major topics and contributors to the field. David Sweatt is certainly a leading authority on the topic and his presentation of the varied aspects of memory research is enjoyable as it is informative. Although this edition (2003)is now superseded by the 2009 edition, the issues are still relevant - making this edition a good buy for those who wish to save money.

0 of 0 people found the following review helpful.
The book meets my need.
By xuefu zhong
The book has been translated in Chinese. The Chinese version was published in 2012.
The book meets my need, I am now working on the subject which is related to the memory of human being.

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Jumat, 26 Februari 2010

[T993.Ebook] Ebook Halt Station India: The Dramatic Tale of the Nation's First Rail Lines, by Rajendra B. Aklekar

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Halt Station India: The Dramatic Tale of the Nation's First Rail Lines, by Rajendra B. Aklekar

Halt Station India chronicles the dramatic rise of India's original rail network, the arrival of the first train, and the subsequent emergence of a pioneering electric line-all in the port city of Bombay. Trains that once provoked awe and fear-they were viewed as fire chariots, smoke-spewing demons-have today become a nation's lifeblood. Taking a walk along India's first rail lines, the author stumbles upon fragments of the past-a clock at Victoria Terminus that offers a rare view of a city; a cannon near Masjid Bunder Station that is worshipped as a god; a watchtower overlooking Sion Station, believed to have housed a witch. Each pit-stop comes with stories of desire and war, ambition and death-by Dockyard Road Station, for instance, author Laurence Sterne's beloved, Eliza Draper, followed a sailor into the sea; or close to Parel Station, the wife of India's governor general, Lord Canning found a garden rich in tropical vegetation; this, she replicated at Barrackpore. Drawing from journals, biographies, newspapers and railway archives-and with nostalgic, first-time accounts of those who travelled by India's earliest trains-the book captures the economic and social revolutions spurred by the country's first train line. In this, Halt Station India is not just about the railways-it is the story of the growth of India's business capital and a rare study of a nation.

  • Sales Rank: #1362121 in Books
  • Published on: 2014-12-01
  • Released on: 2015-01-07
  • Original language: English
  • Dimensions: 8.50" h x .58" w x 5.50" l, .57 pounds
  • Binding: Paperback
  • 227 pages

Review
Rajendra B. Aklekar s research and his scholarship which enables him to interpret his findings throws new light on the way railways were built. --Sir Mark Tully, author of Non-Stop India

Fascinating stuff. An enormous amount of really rigorous work. --Naresh Fernandes, author of City Adrift: A Short Biography of Bombay

About the Author
A journalist for the past twenty years, Rajendra B. Aklekar has two things on his mind the railways and Bombay. He started his career with Rusi Karanjia s firebrand The Daily, where he used to run a weekly column on the history of Bombay s railway stations. Presently, Aklekar is associated with The Times Group s Mumbai Mirror. He has trained himself in museology to document Bombay s vanishing relics, helped the railways set up heritage galleries, and worked on several prestigious projects to conserve the city s ancient structures.

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Jumat, 19 Februari 2010

[D676.Ebook] Download Ebook Rocky Ride: Thompson & Sons, Book 1, by Vivian Arend

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He's got a touch that's hotter than hot.

It took a hell of a lot of fast-talking and more than a few speeding tickets before Mitch Thompson convinced Constable Anna Coleman to take him for a ride. Only now that she's loosened off her stiff RCMP uniform, it's not nearly enough. Their secret sexual escapades are mind blowing, but Mitch wants more than her body, he wants her heart.

Her world could go up in flames.

It's a dangerous road to walk, and Anna doesn't know how far she can safely tread. Bad boy Mitch may have lured her wild side out to play, but giving in to their increasingly passionate desires could endanger her very civilized career. Somewhere between yearning and obsession there has to be a balance point.

Or they're both going to get burned.

  • Sales Rank: #15410 in Audible
  • Published on: 2015-06-12
  • Format: Unabridged
  • Original language: English
  • Running time: 249 minutes

Most helpful customer reviews

133 of 139 people found the following review helpful.
You can't just assume that your audience has read you entire catalog of work
By Amazon Customer
I couldn't get into it. I couldn't forge a connection to the story or it's characters. The beginning of the book reads as if it's a continuation of another book which at first seemed weird since it's book #1 in its series. After checking the author's GR page, I discovered that it is I spin off of a previous series. Nonetheless as an author you can't just assume that your audience has read you entire catalog of work, and not properly introduce them to the characters and the settings with a brief history or recap. You can't just assume your audience will understand your acronyms/initials, make all the necessary connections between characters, and magical know your characters history. The more I read the more frustrated I became and then I realized its Friday night and the last thing I need is frustration.

19 of 20 people found the following review helpful.
Hot start to the series
By Artfullee
3.5 stars
Rocky Ride is the first book in the Thompson and Sons series, a spin off of the Six Pack Ranch books, and the first book I have read by this author. Even though Anna and Mitch have made appearances in other books, this can be read as a standalone, although it has made me curious to go back and read more about this family.

On the outside Anna and Mitch are opposites, she is a RCMP officer, dedicated to her job and having a career in law enforcement. He is one of the town's bad boys, with a reputation to match the tough exterior. When these two get together, sparks fly in their clandestine encounters, passion running at an all time high, each totally focused on the other in those moments. To Anna, these encounters are just that; hot, satisfying sex with no long term commitment or attachment. To Mitch they are becoming only a taste of what he wants long term, and when he decides to ask Anna for more he is unsure of her reaction.

This books jumps right in to the steamy, unadulterated passion these two share. They really heat up the page when they are together, and I did feel the chemistry between Anna and Mitch. I felt the urgency in their lust for each other but I felt I missed out on complete connection to their emotions. I wanted to know a bit more of the backstory of each of the characters so I could invest fully in their romance. Having said that, I liked the way Anna came into her own by looking past the exterior and standing up for Mitch when the town's prejudices and uninformed judgments tried to disrupt their relationship. Anna is one smart woman, only too aware of the harm narrow mindedness can cause, and when she sets her mind on a more permanent relationship with Mitch, she handles the troublemaker with smarts and shrewdness. It was also refreshing to have the male want 'more' and Mitch's list of fantasies were romantic and heartfelt. I really liked the way he set out to win Anna's heart, gain her trust and forge a committed relationship.

Overall I enjoyed this book and will be reading the next in the series

7 of 7 people found the following review helpful.
Rocky Ride
By Evampire
Straight laced girls being lured to the wild side by bad boys in this riveting and sexy contemporary romance. Anna’s increasingly passionate desires could endanger her very civilized career and Mitch wants more than their secret sexual escapades – he wants her heart. Will they both get burned?

This fast paced and smooth flowing plot gets the adrenaline flowing with some red hot mind-blowing passion and some intrigue. The author describes the story in well written scenes and details that capture the imagination and draws the reader deeper into the story and a co-worker with questionable motives adds some drama and suspense to the story. The characters are strong, compelling, easily related to and draw the reader deeper into the story with their sexual exploits and relationship drama.

The attraction between Mitch and Anna is super hot and burns up the pages and their frequent and increasingly passionate sex scenes scorch the reader with their fiery intensity. As the couple explore their sexual desires they engage in a little bdsm, spanking and voyeurism that really spices things up. The relationship is slow to build due to Anna’s worry over letting go, but as she discovers her sensual nature, it gets harder for to deny Mitch’s desire for more.
Anna’s job as quite a bit of drama to the story, not only because her increasing sexual cravings for Mitch causes some inappropriate public displays but because there is a co-worker who is sure that Mitch is bad news.

Appearances can be deceiving and you should never judge a book by its cover… well in the case of this one, you should because let’s face it you don’t want to miss out on this enticing and sexy story. I mean what’s not like about tattooed, motorcycle riding hotties.

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Rabu, 17 Februari 2010

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  • Binding: Hardcover

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Minggu, 07 Februari 2010

[C825.Ebook] Download Ebook Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz

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Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz

In the last few years, courses on parallel computation have been developed and offered in many institutions in the UK, Europe and US as a recognition of the growing significance of this topic in mathematics and computer science. There is a clear need for texts that meet the needs of students and lecturers and this book, based on the author's lecture at ETH Zurich is an ideal practical student guide to scientific computing on parallel computers working up from a hardware instruction level, to shared memory machines and finally to distributed memory machines. Aimed at advanced undergraduate and graduate students in applied mathematics, computer science and engineering, subjects covered include linear algebra, fast Fourier transform, and Monte-Carlo simulations, including examples in C and in some cases Fortran. This book is also ideal for practitioners and programmers.

  • Sales Rank: #1462113 in Books
  • Published on: 2004-03-25
  • Original language: English
  • Number of items: 1
  • Dimensions: 6.10" h x .60" w x 9.20" l, .96 pounds
  • Binding: Paperback
  • 288 pages

Review

"This book is unique in thta it provides a balanced treatment of the concepts of parallelism on all levels...For computer science undergraduates learning about parallelism and for those who develop programs and systems that exploit as much parallelism as possible so as to maximize the desired performance."--Choice


About the Author
Peter Arbenz is at Institute for Scientific Computing, Department Informatik, Ethz, Switzerland. Wesley Petersen is at Seminar for Applied Mathematics, Department of Mathematics, Ethz, Switzerland.

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Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz PDF
Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz EPub
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Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz iBooks
Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz rtf
Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz Mobipocket
Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz Kindle

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[C825.Ebook] Download Ebook Introduction to Parallel Computing (Oxford Texts in Applied and Engineering Mathematics), by W. P. Petersen, P. Arbenz Doc
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